Quantitative trait loci ( QTL ) m apping in multi - line crosses of
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چکیده
منابع مشابه
Combining data from multiple inbred line crosses improves the power and resolution of quantitative trait loci mapping.
Rodent inbred line crosses are widely used to map genetic loci associated with complex traits. This approach has proven to be powerful for detecting quantitative trait loci (QTL); however, the resolution of QTL locations, typically approximately 20 cM, means that hundreds of genes are implicated as potential candidates. We describe analytical methods based on linear models to combine informatio...
متن کاملLinkage analysis of microsatellite markers on chromosome 5 in an F2 population of Japanese quail to identify quantitative trait loci affecting carcass traits
An F2 Japanese quail population was developed by crossing two strains (wild and white) to map quantitative trait loci (QTL) for performance and carcass traits. A total of 472 F2 birds were reared and slaughtered at 42 days of age. Performance and carcass traits were measured on all of the F2 individuals. Parental (P0), F1 and F2 individuals were genotyped with 3 microsatellites from quail chrom...
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Body weight (BW) and carcass traits are complex and important economic traits that may benefit from the implementation of MAS. The objective of the current study was to identify QTL associated with BW and carcass traits in an experimental half-sib cross of Japanese quails selected for BW at 4 weeks of age. Body weight and carcass traits were measured in the F2 population. Total F2 individuals a...
متن کاملCombining different line crosses for mapping quantitative trait loci using the identical by descent-based variance component method.
Mapping quantitative trait loci (QTLs) is usually conducted with a single line cross. The power of such QTL mapping depends highly on the two parental lines. If the two lines are fixed for the same allele at a putative QTL, the QTL is undetectable. On the other hand, if a QTL is segregating in the line cross and is detected, the estimated variance of the QTL cannot be extrapolated beyond the st...
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Quantitative trait loci (QTL) influencing body weight were mapped by linkage analysis in crosses between a high body weight selected line (DU6) and a control line (DUKs). The two mouse lines differ in body weight by 106% and in abdominal fat weight by 100% at 42 days. They were generated from the same base population and maintained as outbred colonies. Determination of line-specific allele freq...
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